STUDY ON THE SYNTHESIS OF β-NITROAMINES VIA AZA-HENRY REACTION

Authors

  • Anh Thuc Bui Le Quy Don Technical University
  • Hai Thuong Cao Le Quy Don Technical University
  • Thuy Trang Bui Military Academy of Logistics

DOI:

https://doi.org/10.56651/lqdtu.jst.v14.n1.462

Keywords:

Aza-Henry reaction; amine; imine; β-nitroamine.

Abstract

Aza-Henry is one of effective and fundamental carbon-carbon bond-forming reactions in organic chemistry. This reaction is also a useful method for preparation of versatile compounds containing nitrogen atom as well as for the synthesis of many bioactive molecules. The objective of this paper was to investigate the synthesis of β-nitroamines in mild conditions using inexpensive NaHCO3 as a catalyst. This process was efficient and compatible with a wide range of imines to afford a direct access to β-nitroamine compounds in very good yields up to 89% and high selectivities.

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Published

2022-10-27

How to Cite

Bui, A. T., Cao, H. T. ., & Bui, T. T. . (2022). STUDY ON THE SYNTHESIS OF β-NITROAMINES VIA AZA-HENRY REACTION. Journal of Science and Technique, 14(01). https://doi.org/10.56651/lqdtu.jst.v14.n1.462

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